Chronic Rhinosinusitis: Potential Role of Microbial Dysbiosis and Recommendations for Sampling Sites
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منابع مشابه
Chronic Rhinosinusitis: Potential Role of Microbial Dysbiosis and Recommendations for Sampling Sites
Chronic rhinosinusitis (CRS) is an inflammatory condition that affects up to 12% of the human population in developed countries. Previous studies examining the potential role of the sinus bacterial microbiota within CRS infections have found inconsistent results, possibly because of inconsistencies in sampling strategies. The aim of this study was to determine whether the sinus microbiome is al...
متن کاملChronic rhinosinusitis: a microbiome in dysbiosis and the search for alternative treatment options
Amanda Bordin , Hanna E Sidjabat , Kyra Cottrell and Anders Cervin The University of Queensland, UQ Centre for Clinical Research, Herston, Qld 4029, Australia The University of Queensland, School of Medicine, Brisbane, Qld, Australia Department of Otolaryngology, Head and Neck Surgery, Royal Brisbane and Women’s Hospital, Brisbane, Qld, Australia Corresponding author. Tel: +61 7 3346 6073, Fax:...
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Thousands of bacterial phylotypes colonise the human body and the host response to this bacterial challenge greatly influences our state of health or disease. The concept of infectogenomics highlights the importance of host genetic factors in determining the composition of human microbial biofilms and the response to this microbial challenge. We hereby introduce the term 'genetic dysbiosis' to ...
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Collective clinical and bench observations of the past 25 years have expanded interest in the role that fungi may play in developing and perpetuating inflammatory disease of the respiratory tract. As with any new concept, controversy regarding such a process has emerged, but it has served to stimulate increased interest and further study. Review of the current literature appears to offer strong...
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There has been considerable investigation of host-microbial interactions in patients with chronic rhinosinusitis (CRS) in hopes of elucidating mechanisms of disease and better treatment. Most attention has been paid to bacterial infection and potential underlying defects in innate immunity. Bacterial biofilm is present in most patients with CRS undergoing surgical intervention, and its presence...
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ژورنال
عنوان ژورنال: Frontiers in Cellular and Infection Microbiology
سال: 2018
ISSN: 2235-2988
DOI: 10.3389/fcimb.2018.00057